Solubility Enhancement

Many APIs, especially newly developed ones, present higher degree of lipophilicity and poor water solubility. These characteristics limit their oral bioavailability and, hence, their potential to be formulated in a suitable dosage form.

At Pensatech Pharma we make use of different technologies to allow the delivery of poorly soluble drugs. With the use of different formulation strategies and the selection of appropriate excipients we are able to develop an effective and marketable product. Our solubility enhancement technologies include:

  • Oily emulsions

  • Micro- and Nano-suspensions

  • Solid solutions and dispersions

  • Hot melt extrusion (HME)

  • Spray dried dispersions (SDD)

 

Contact us to learn more about our capabilities and to discuss how we can help you solve your challenges