Formulation & Process Development
At Pensatech Pharma we use our extensive experience in formulation and process development to identify and solve different challenges. We create a tailored formulation and process development program using a broad range of capabilities to proactively manage our customers’ requests. Our services include:
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Contract formulation development services, which offer tailor-made formulation solutions to the specific needs of our clients
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Solution of complex formulation challenges
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Formulation design and DDS technology selection: Rationale selection of dosage form, formulation and processes based on expertise in drug delivery and biopharmaceutics
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Defining target release profile based on PK analysis
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Risk-based approach to decision making within a Quality-by-Design (QbD) framework
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Formulation and Process development:
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Feasibility studies
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Formulation concept studies to support in vivo assessment (PK study)
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Development of enabling formulations for rapid evaluation in the clinic
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Development of commercialisable formulations
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Full development
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Product transfer and industrial scale up with partnering contract manufacturers
Our technologies include:
Modified release systems
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Extended release drug delivery systems
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Multiparticulates (granules, pellets)
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Minitablets
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Single unit tablets
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Osmotic tablets
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Matrix and coated systems
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Hydrophilic and lipophilic polymeric matrix and coating materials
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High dose extended release drug delivery systems
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Fixed dose combinations with independent release adjustment for each API
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Dual release systems (immediate + extended release combination)
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Reduced food effect (robustness against intestinal forces and fluids and food / food degradation products)
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Enteric/ colonic delivery dosage forms
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Pulsatile drug delivery
Parenterals
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Depot suspensions (micronized/milled API; Nano-suspensions)
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Emulsions / Nano-emulsions
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Microparticles
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Implants (HME and in-situ forming)
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Liposomes
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Biodegradable polymeric and lipidic carriers
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Lyophilization
Specialized drug delivery techniques
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Paediatric and geriatric dosage forms (multiparticulates, taste masking)
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Orally disintegrating tablets (ODT) or fast dissolving/disintegrating dosage forms (FDDF) (tablets, lyophilized products)
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Delivery of unstable drugs
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Delivery of poorly water-soluble drugs
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Microencapsulated products
Classical pharmaceutical dosage forms
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Solid oral dosage forms
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Granules, Pellets, Tablets and Capsules
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Coating systems (Aqueous- and solvent-based)
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Modified release, Taste masking and Moisture protection
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Liquid and semisolid formulations
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Aqueous and oily solutions, emulsions, suspensions and gels
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Please click here to have a look at our processing capabilities. For further information on our formulation and process development services, please contact us.